"Luzer" is something like an eternal loser. Accent in the word "Luzer" is put on the letter "y". Literally, Loser is translated from English as "the one who always loses" (from the verb to lose ).
In this difference in translations, as some clever people have noticed, there is a difference between Russian and American mentality:
"Loser" is just someone who does not carry,
and "Luzer" - a man who always lost in the fight. That is, we-Russians are accustomed to write off their failures for lack of luck, while in the west failures are regarded as an inability to overcome, overcome difficulties.
Luzer is in the list: Slang